Group/Corporate Codes
Wyndham Houston Medical Center Exterior

Special Offers

Located in the heart of the Texas Medical Center, our full-service hotel accommodating both short and long-term stays with stylish rooms, modern décor, and thoughtful lifestyle amenities, such as free Wi-Fi, shuttle service and affordable self-parking and valet parking. Guests will enjoy our seasonal outdoor pool and fitness center. We offer convenient business amenities, like print, copy, and fax services and meeting space for up to 10 people. Room service is available daily, or dine in at our onsite restaurant, Main Street Bar and Grill, for breakfast, lunch and dinner.

Houston Hotel Deals That Are Out of This World

From weekend getaways to dining specials, we've got you covered with exciting hotel packages that help you experience Houston in luxury. Enjoy delicious food, drinks, parking and beautiful accommodations that put you in the heart of Houston's vibrant medical and museum district.

Book Direct for Our Best Rates & Points!

Book directly on our website to receive our guaranteed best rates! Plus, if you are a Wyndham Rewards member, you’ll also earn Wyndham Rewards points that you can redeem for future vacations.

Downtown Concert & Event Parking Package

Experience exciting downtown Houston sports, concerts or events and stay close to the action to make your night easier. Better yet, sleep in and enjoy late check-out.

Family Time Kid Approved

Pack your bags and take an adventure with the entire family.

Light Rail Package

Experience the Houston Light Rail when traveling between Downtown Houston and NRG Center.