Modern Accomodations In
The Heart Of Houston’s Medical Center

Welcome to Wyndham Houston - Medical Center Hotel & Suites

Wyndham Houston - Medical Center Hotel & Suites is the perfect home base while visiting the Space City. Our unrivaled location—across the street from world-renowned Texas Medical Center—is just minutes from Houston’s best attractions, universities, and the Museum District. Reach your destination with ease—our complimentary shuttle offers friendly door-to-door service to Texas Medical Center, MD Anderson Cancer Center, UT Health Science Center, and the Texas Children’s Hospital. While Rice University, The University of Houston, Texas Southern University, and nearby attractions are just a short walk or METRO ride away. Our warm service, thoughtful amenities, and commitment to comfort and cleanliness make us the best choice for your Houston stay.

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Top reasons to stay

In The Heart of Houston’s Medical Center

Texas Medical Center—home to the brightest minds in medicine, the largest children’s hospital, and the world’s largest cancer hospital—is conveniently located across the street.

Top Reasons To Stay

Spacious Suites

Our spacious suites offer plenty of room for relaxing, recharging, and resting in comfort. Stretch out and enjoy the extra space—each suite features kitchens or kitchenettes and brightly lit workspaces to make you feel at home.

Top Reasons To Stay

Extended Stay Available

Drop your bags and settle in—we are one of the best extended stay hotels in Houston. Experience everything Houston has to offer with home-like amenities. Prepare a meal in your kitchen, relax in your bright and airy living room, rest easy in your home away from home.

Top Reasons To Stay

Shuttle Transportation

Our reliable shuttle service will drop you at any of the hospitals in Texas Medical Center. Nothing says Texas-hospitality like door-to-door service at your fingertips.

Top Reasons To Stay

Proximity To Attractions

Discover the charms of the Space City from our central location—Houston is a cultural hub for dining, museums, history, and so much more. Explore the nearby attractions with the utmost walkability and ease, or hop on the METRO, just minutes from our doorstep.



Better Nights Of Sleep Begin Here

Sleep is the key to health and wellness—experience bedtime bliss in our comfortable rooms that feature plush bedding, luxe amenities, and all of the essentials for short and extended stays.

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Make Yourself At Home

Extended Stays

Comfort is one of the most important features of an extended stay—that’s why our thoughtfully designed suites include kitchens, wood cabinetry, separate contemporary living areas, plush bedding, and more. Pair that with health-conscious amenities—outdoor pool and fitness center—for a Houston stay to remember.

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Guests Say It Best

  • Wonderful Breakfast Buffet

    “Hotel is centrally located near major medical centers. It was wonderful to have a free medical shuttle all day long with courteous and well-informed drivers. Hotel staff was personable and efficient. Do not miss the wonderful breakfast buffet.”
    - Kay G
  • Medical Trip

    “Excellent location with good prices. Overall clean hotel with comfortable beds. Everyone was very friendly and helpful from the shuttle drivers to the front desk”.
    - J&TSanders
  • We Can Always Count On Wyndham

    “When we have to travel to the Medical Center in Houston we stay at the Wyndham in the Medical Center. We are treated very well. The rooms are always clean. If we have a problem it is resolved in a timely manner.”
    - Jeannine B
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Front & Center In Houston’s Medical Center

Our unbeatable location is across the street from the world-renowned Texas Medical Center, and within walking distance of Houston’s Museum District, the Houston Zoo, and Rice University.


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