Group/Corporate Codes
Wyndham Houston Medical Center Exterior

Special Offers

Located in the heart of the Texas Medical Center, our full-service hotel accommodating both short and long-term stays with stylish rooms, modern d├ęcor, and thoughtful lifestyle amenities, such as free Wi-Fi, shuttle service and affordable self-parking and valet parking. Guests will enjoy our seasonal outdoor pool and fitness center. We offer convenient business amenities, like print, copy, and fax services and meeting space for up to 10 people. Room service is available daily, or dine in at our onsite restaurant, Main Street Bar and Grill, for breakfast, lunch and dinner.

Houston Hotel Deals That Are Out of This World

From weekend getaways to dining specials, we've got you covered with exciting hotel packages that help you experience Houston in luxury. Enjoy delicious food, drinks, parking and beautiful accommodations that put you in the heart of Houston's vibrant medical and museum district.


In honor of the #EverydayHeroes fighting on the front lines of COVID-19, Wyndham Rewards is offering all essential workers a complimentary GOLD membership upgrade. This includes truck drivers, delivery drivers, warehouse workers, construction workers, sanitation workers, grocery associates, healthcare workers, and more.